ATIVAN (LORAZEPAM)
Ativan is a well-known drug from the group of benzodiazepine derivatives, which are extensively used for the treatment of a large spectrum of mental health problems from sleeping problems to epileptic seizures. According to the directions to be used, Ativan additionally has a calming and enjoyable effect.
The drug is relevant for neurosis and nervousness states accompanied by somatic problems, insomnia and panic assaults. It additionally has an anticonvulsant and muscle relaxant impact.
PHARMACODYNAMICS AND PHARMACOKINETICS
Pharmachologic effect of Lorazepam is as a end result of of its similarity with gamma-aminobutyric acid (GABA). Lorazepam belongs to the class of benzodiazepine derivatives and impacts the CNS constructions, liable for the regulation of emotional activity (these are limbic system and hypothalamus). The drug supplies the flow of chlorine into the excited neuron, which in turn stabilizes neuron.
- anxiolytic
- sleeping drug
- anticonvulsant
- muscle relaxant
Active substance is well absorbed from the digestive tract, reaching its maximum focus in the patient’s blood 2 hours later.
INDICATIONS AND CONTRAINDICATIONS
Ativan is broadly used within the trendy medicine for the remedy of such states and psychological diseases:
- psychosis
- various phobias
- psychosomatic disorders
- epilepsy
- panic attacks
- obsessive-compulsive syndrome
- mental problems related to injuries
- behavioral disorders
- sleep disorders
- headache attributable to increased emotional stress and tension
- nervousness and anxiety
- consequences of the shock experienced
- sickness and vomiting, triggered by a course of chemotherapy
Also, Ativan can be utilized as a component of combination remedy through the remedy of chronic alcohol dependancy. Sometimes, it is prescribed together with analgesic medicines to arrange the patients for operative or diagnostic interventions.
Ativan is utilized in drugs to get rid of the symptoms of psychological illnesses:
- nervousness
- increased anxiety
- tremor
- insomnia
- psychosis
- alcohol delirium
- cramps
- paralysis
- athetosis
Ativan is a robust substance; subsequently, it’s strictly forbidden to the sufferers, which have the next concomitant ailments and circumstances:
- hypersensitivity to the lively substance or auxiliary components
- intolerance to different drugs with an analogous mechanism of action
- myasthenia
- glaucoma
- intoxication with substances depressing the central nervous system
- breathing problems
- liver failure
- apnea syndrome
- depression
- addiction to medication, nicotine and alcohol (except withdrawal syndrome)
- alcohol intoxication
- acute renal failure
The use of Ativan is strictly forbidden to pregnant and breastfeeding women. If the utilization of Lorazepam is crucial for the mother’s health, she should cease breastfeeding for the time of remedy with this medication. Also, this treatment is forbidden to the minor patients. Elderly sufferers should take Lorazepam with nice caution and carefully monitor the body’s response to the drug.
The use of Ativan can affect the patient’s response fee. Therefore, through the treatment, you should chorus from driving and managing other complicated mechanisms and limit the work requiring caution.
DOSAGE
According to the instructions for use, you should begin the therapy with Ativan with the bottom effective dose, and the course should not be lengthy. With a large dosage and long course, such substances can make the patient addicted. In case of abrupt withdrawal of Ativan, likelihood is that the patient could expertise withdrawal or rebound syndrome; therefore, it is essential to cease the course by steadily lowering the drug dose.
Leave a Comment